Michael-Stork addition of cyclopentyl enamine to allenyl ketones and esters.
نویسندگان
چکیده
[Chemical reaction: see text] We report the first examples of a Michael-Stork enamine addition to allenyl esters and ketones. Studies reveal that 2 equivalents of enamine are required for optimal yields. In the case of an allenyl methyl ketone, cyclopentyl enamine addition led to 8-oxobicyclo[3.2.1]octane formation, providing evidence for the in situ formation of an enamine intermediate following the initial Michael-Stork reaction.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 70 20 شماره
صفحات -
تاریخ انتشار 2005